mitragynine
noun
mi·trag·y·nine
mi-ˈtra-jə-ˌnēn 
: the principal psychoactive indole alkaloid C23H30N2O4 that is found in kratom and that binds as an agonist to certain opioid receptors to produce effects (such as analgesia) similar to that of opioids
Kratom contains more than 40 phytochemicals in the class of indole alkaloids, the primary one being mitragynine …—
David Kiefer
David KieferBags of powder line the shelves at Laughing Lion, each with a varying level of mitragynine, the compound that interacts with opioid receptors in the brain, and is said to produce those good feelings, alertness, decreased pain or relaxation, depending on the amount.—Jennifer Mulson
compare 7-hydroxymitragynine
Jennifer MulsonExamples of mitragynine in a Sentence
Recent Examples on the Web
One of the key constituents of kratom is an organic compound called mitragynine.
—C. Michael White, The Conversation, 20 Feb. 2024
The plant’s potent effects are attributed to its distinct alkaloid profile, which includes higher levels of 7-hydroxy mitragynine and mitragynine compared to other kratom varieties.
—Sponsored Content, The Mercury News, 16 Feb. 2024
The main kind of Kratom alkaloid, mitragynine, is a partial agonist for the mu-opioid signals [1].
—Sponsored Content, The Mercury News, 19 Jan. 2024
Two of these alkaloids, mitragynine and 7-hydroxymitragynine, are especially popular due to their effects.
—Amber Smith, Discover Magazine, 20 Dec. 2022
Those with high metabolic rates and high body fat may feel the effects of kratom faster, as mitragynine is a fat-soluble alkaloid and high metabolic rates coincide with faster body processes, including digestion.
—Dallas News, 10 Nov. 2022
Scientists say the main kratom ingredients − mitragynine and 7-hydroxymitragynine − partly activate brain receptors that addictive drugs do.
—Ken Alltucker, USA TODAY, 27 May 2023
The reason of its tremendous popularity is the alkaloids mitragynine and 7-hydroxymitragynine, which have shown to be extremely strong components.
—Amber Smith, Discover Magazine, 25 Dec. 2022
All of these tablets have 100 milligrams of mitragynine, and they are made with top-quality kratom extract standardized to 45%.
—Amber Smith, Discover Magazine, 15 Dec. 2022
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C. Michael White, The Conversation, 20 Feb. 2024
The plant’s potent effects are attributed to its distinct alkaloid profile, which includes higher levels of 7-hydroxy mitragynine and mitragynine compared to other kratom varieties.
—Sponsored Content, The Mercury News, 16 Feb. 2024
The main kind of Kratom alkaloid, mitragynine, is a partial agonist for the mu-opioid signals [1].
—Sponsored Content, The Mercury News, 19 Jan. 2024
Two of these alkaloids, mitragynine and 7-hydroxymitragynine, are especially popular due to their effects.
—Amber Smith, Discover Magazine, 20 Dec. 2022
Those with high metabolic rates and high body fat may feel the effects of kratom faster, as mitragynine is a fat-soluble alkaloid and high metabolic rates coincide with faster body processes, including digestion.
—Dallas News, 10 Nov. 2022
Scientists say the main kratom ingredients − mitragynine and 7-hydroxymitragynine − partly activate brain receptors that addictive drugs do.
—Ken Alltucker, USA TODAY, 27 May 2023
The reason of its tremendous popularity is the alkaloids mitragynine and 7-hydroxymitragynine, which have shown to be extremely strong components.
—Amber Smith, Discover Magazine, 25 Dec. 2022
All of these tablets have 100 milligrams of mitragynine, and they are made with top-quality kratom extract standardized to 45%.
—Amber Smith, Discover Magazine, 15 Dec. 2022
Dictionary Entries Near mitragynine
Cite this Entry
“Mitragynine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/mitragynine. Accessed 28 Nov. 2024.
Copy CitationMedical Definition
mitragynine
noun
mi·trag·y·nine
mi-ˈtraj-ə-ˌnēn
: the principal psychoactive indole alkaloid C23H30N2O4 that is found in kratom and that binds as an agonist to certain opioid receptors to produce effects (such as analgesia) similar to that of opioids
Withdrawal from chronic mitragynine induces opioid-like somatic withdrawal, locomotor hypersensitivity for further pharmacological stimulation and enhances anxiety levels for up to 48 hours.—Nurul H. M. Yusoff et al., Addiction Biology
compare 7-hydroxymitragynine
Nurul H. M. Yusoff et al., Addiction BiologyLove words? Need even more definitions?
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