agonist

noun

ag·​o·​nist ˈa-gə-nist How to pronounce agonist (audio)
1
: one that is engaged in a struggle
2
[from antagonist]
a
: a muscle that is controlled by the action of an antagonist with which it is paired
b
: a chemical substance capable of combining with a specific receptor on a cell and initiating the same reaction or activity typically produced by the binding endogenous substance
dopaminergic agonists
compare antagonist sense 2b

Examples of agonist in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The conversation around expectations is more nuanced with massive weight loss patients—those who have, with the help of GLP-1 agonists, bariatric surgery, and/or lifestyle modifications, shed at least half of their excess weight. Jolene Edgar, Allure, 20 Nov. 2024 One of the most prominent medical developments in recent years has been the emergence of a class of drugs called glucagon-like peptide-1 receptor agonists (GLP-1 RAs). Tom Hawking, Popular Science, 17 Oct. 2024 Of note: Only 18% of firms with 200 or more workers offering health benefits cover GLP-1 agonists for weight loss. Maya Goldman, Axios, 9 Oct. 2024 These medications are classified as GLP-1 receptor agonists. Karen Berger, Pharmd, Verywell Health, 24 Oct. 2024 See all Example Sentences for agonist 

Word History

Etymology

borrowed from Late Latin agōnista, borrowed from Greek agōnistḗs, from agōnízesthai "to contend, fight" + -istēs -ist entry 1 — more at agonize

First Known Use

1658, in the meaning defined at sense 1

Time Traveler
The first known use of agonist was in 1658

Dictionary Entries Near agonist

Cite this Entry

“Agonist.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/agonist. Accessed 30 Nov. 2024.

Medical Definition

agonist

noun
ag·​o·​nist ˈag-ə-nəst How to pronounce agonist (audio)
1
: a muscle that on contracting is automatically checked and controlled by the opposing simultaneous contraction of another muscle

called also agonist muscle, prime mover

compare antagonist sense a, synergist sense 2
2
: a chemical substance (as a drug) capable of combining with a receptor on a cell and initiating the same reaction or activity typically produced by the binding of an endogenous substance
binding of adrenergic agonists
compare antagonist sense b

More from Merriam-Webster on agonist

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