1
as in plague
a widespread disease resulting in a high rate of death
one of the great pests of the 20th century was the influenza epidemic of 1918, which killed millions across the globe
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2
as in nuisance
one who is obnoxiously annoying
stop being a pest to your sister and go find something else to do
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3
as in headache
something that is a source of irritation
a never-ending construction project that continues to be a pest for motorists
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Merriam-Webster unabridged
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