as in pains
a state of great suffering of body or mind
as a new teacher, she was in real anguish over the decision to report the cheating
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1
as in plagues
to cause persistent suffering to
she was anguished by the fear that her sons would die in the war
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2
as in grieves
to feel deep sadness or mental pain
I anguished over the loss of my father for years afterwards
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Merriam-Webster unabridged
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