tumor suppressor gene
noun
: any of a class of genes (such as p53) that act in normal cells to inhibit unrestrained cell division and that when inactivated (as by mutation) place the cell at increased risk for malignant proliferation
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“Tumor suppressor gene.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/tumor%20suppressor%20gene. Accessed 28 Nov. 2024.
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tumor suppressor gene
noun
variants
or tumor-suppressor gene
: any of a class of genes (as p53 and APC) that act in normal cells to inhibit unrestrained cell division and that when inactivated (as by mutation) place the cell at increased risk for malignant proliferation
In some cases [of cancer], growth-inhibiting genes called tumor suppressor genes are damaged, allowing cells to proliferate unchecked.—
Faye Flam, The Philadelphia Inquirer
Faye Flam, The Philadelphia InquirerIn most human-cancer cells, there are multiple mutations—some that activate oncogenes and some that silence tumor-suppressor genes.—Robert A. Weinberg and Anthony L. Komaroff, Newsweek
Robert A. Weinberg and Anthony L. Komaroff, Newsweekcalled also anti-oncogene
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