thalidomide

noun

tha·​lid·​o·​mide thə-ˈli-də-ˌmīd How to pronounce thalidomide (audio) -məd How to pronounce thalidomide (audio)
: a drug C13H10N2O4 that was formerly used as a sedative and is now used as an immunomodulatory agent especially in the treatment of leprosy and multiple myeloma and that is known to cause malformations of infants born to mothers using it during pregnancy

Examples of thalidomide in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
See, everybody knew that thalidomide was round and about. Katie Hafner, Scientific American, 17 Oct. 2024 Just how many pregnant people might have thalidomide in their medicine cabinet? Katie Hafner, Scientific American, 3 Oct. 2024 The doctor noted how everyone said thalidomide was remarkably non-toxic. Katie Hafner, Scientific American, 19 Sep. 2024 Their mothers, on doctors’ orders, had taken thalidomide during pregnancy to stop morning sickness. Dan Piepenbring, Harper's Magazine, 30 Mar. 2024 See all Example Sentences for thalidomide 

Word History

Etymology

phthalic acid + -id- (from imide) + -o- + imide

First Known Use

1958, in the meaning defined above

Time Traveler
The first known use of thalidomide was in 1958

Dictionary Entries Near thalidomide

Cite this Entry

“Thalidomide.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/thalidomide. Accessed 30 Nov. 2024.

Medical Definition

thalidomide

noun
tha·​lid·​o·​mide thə-ˈlid-ə-ˌmīd How to pronounce thalidomide (audio) -məd How to pronounce thalidomide (audio)
: a sedative, hypnotic, and antiemetic drug C13H10N2O4 that was formerly used chiefly in Europe during the late 1950s and early 1960s especially to treat morning sickness but was soon withdrawn after being shown to cause serious malformations (as missing or severely shortened arms and legs) in infants born to mothers using it during the first trimester of pregnancy and that is now used as an immunomodulatory agent chiefly in the treatment of cutaneous complications of leprosy and in combination with dexamethasone in the treatment of multiple myeloma

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