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sclerosis
noun
scle·ro·sis
sklə-ˈrō-səs
1
: pathological hardening of tissue especially from overgrowth of fibrous tissue or increase in interstitial tissue
also
: a disease characterized by sclerosis
2
: an inability or reluctance to adapt or compromise
political sclerosis
Examples of sclerosis in a Sentence
Recent Examples on the Web
The nightmare scenario would be a zone of important but depopulating economies, accounting for much of the world’s output, frozen into perpetual sclerosis or decline by pessimism, anxiety, and resistance to reform.
—Nicholas Eberstadt, Foreign Affairs, 10 Oct. 2024
Frequently Asked Questions Multiple sclerosis (MS) symptoms typically start in young adulthood, between 20 and 40 years old.
—Brandi Jones, Msn-Ed, Rn-Bc, Health, 24 Sep. 2024
Autoimmune conditions: Certain autoimmune disorders—such as rheumatoid arthritis (RA), Crohn's disease, connective tissue disorders, systemic sclerosis, and scleroderma—can affect the structure and function of the esophagus and cause odynophagia.
—Lindsay Curtis, Health, 13 July 2024
This includes conditions like rheumatoid arthritis, psoriatic arthritis, Sjögren syndrome, systemic sclerosis, polymyalgia rheumatica, mixed connective tissue disease, dermatomyositis, polymyositis, polyarteritis nodosa, or vasculitis.
—Anuradha Varanasi, Forbes, 29 Mar. 2024
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Word History
Etymology
Middle English sclirosis tumor, from Medieval Latin, from Greek sklērōsis hardening, from sklēroun to harden, from sklēros
First Known Use
1846, in the meaning defined at sense 1
Phrases Containing sclerosis
Dictionary Entries Near sclerosis
Cite this Entry
“Sclerosis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/sclerosis. Accessed 28 Nov. 2024.
Kids Definition
sclerosis
noun
scle·ro·sis
sklə-ˈrō-səs
: an abnormal hardening of a tissue or body part (as arteries or muscles) that occurs in several serious diseases compare multiple sclerosis
Medical Definition
sclerosis
noun
scle·ro·sis
sklə-ˈrō-səs
plural scleroses
-ˌsēz
1
: a pathological condition in which a tissue has become hard and which is produced by overgrowth of fibrous tissue and other changes (as in arteriosclerosis) or by increase in interstitial tissue and other changes (as in multiple sclerosis)
called also hardening
2
: any of various diseases characterized by sclerosis
—usually used in combination
see arteriosclerosis, multiple sclerosis, myelosclerosis
More from Merriam-Webster on sclerosis
Nglish: Translation of sclerosis for Spanish Speakers
Britannica English: Translation of sclerosis for Arabic Speakers
Britannica.com: Encyclopedia article about sclerosis
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