sclerosis

noun

scle·​ro·​sis sklə-ˈrō-səs How to pronounce sclerosis (audio)
1
: pathological hardening of tissue especially from overgrowth of fibrous tissue or increase in interstitial tissue
also : a disease characterized by sclerosis
2
: an inability or reluctance to adapt or compromise
political sclerosis

Examples of sclerosis in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The nightmare scenario would be a zone of important but depopulating economies, accounting for much of the world’s output, frozen into perpetual sclerosis or decline by pessimism, anxiety, and resistance to reform. Nicholas Eberstadt, Foreign Affairs, 10 Oct. 2024 Frequently Asked Questions Multiple sclerosis (MS) symptoms typically start in young adulthood, between 20 and 40 years old. Brandi Jones, Msn-Ed, Rn-Bc, Health, 24 Sep. 2024 Autoimmune conditions: Certain autoimmune disorders—such as rheumatoid arthritis (RA), Crohn's disease, connective tissue disorders, systemic sclerosis, and scleroderma—can affect the structure and function of the esophagus and cause odynophagia. Lindsay Curtis, Health, 13 July 2024 This includes conditions like rheumatoid arthritis, psoriatic arthritis, Sjögren syndrome, systemic sclerosis, polymyalgia rheumatica, mixed connective tissue disease, dermatomyositis, polymyositis, polyarteritis nodosa, or vasculitis. Anuradha Varanasi, Forbes, 29 Mar. 2024 See all Example Sentences for sclerosis 

Word History

Etymology

Middle English sclirosis tumor, from Medieval Latin, from Greek sklērōsis hardening, from sklēroun to harden, from sklēros

First Known Use

1846, in the meaning defined at sense 1

Time Traveler
The first known use of sclerosis was in 1846

Dictionary Entries Near sclerosis

Cite this Entry

“Sclerosis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/sclerosis. Accessed 28 Nov. 2024.

Kids Definition

sclerosis

noun
scle·​ro·​sis sklə-ˈrō-səs How to pronounce sclerosis (audio)
: an abnormal hardening of a tissue or body part (as arteries or muscles) that occurs in several serious diseases compare multiple sclerosis

Medical Definition

sclerosis

noun
scle·​ro·​sis sklə-ˈrō-səs How to pronounce sclerosis (audio)
plural scleroses -ˌsēz How to pronounce sclerosis (audio)
1
: a pathological condition in which a tissue has become hard and which is produced by overgrowth of fibrous tissue and other changes (as in arteriosclerosis) or by increase in interstitial tissue and other changes (as in multiple sclerosis)

called also hardening

2
: any of various diseases characterized by sclerosis
usually used in combination
see arteriosclerosis, multiple sclerosis, myelosclerosis

More from Merriam-Webster on sclerosis

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