inosine

noun

ino·​sine ˈi-nə-ˌsēn How to pronounce inosine (audio) ˈī- How to pronounce inosine (audio)
-sən
: a nucleoside C10H12N4O5 that is composed of hypoxanthine and ribose, that in the form of its monophosphate is a biosynthetic precursor of both AMP and its guanosine analog, and that binds to adenine, cytosine, or uracil especially in some transfer RNAs compare poly i entry c

Examples of inosine in a Sentence

Recent Examples on the Web
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As Bass and a colleague discovered in the late 1980s, cells often replace one building block in their mRNA molecules, adenosine, with another molecule known as inosine. Bymitch Leslie, science.org, 24 Oct. 2024 By replacing the adenosine with inosine, ADARs can essentially correct the mistake, because the cell’s proteinmaking machinery reads the inosine in the mRNA as a guanosine. Bymitch Leslie, science.org, 24 Oct. 2024 These proteins bind to RNAs and alter their sequence by changing a familiar base known as adenosine into a molecule called inosine. Sara Reardon, Scientific American, 5 Feb. 2020 Although not one of the canonical RNA bases, inosine is read by the cell’s protein-translation machinery as the familiar guanosine. Sara Reardon, Scientific American, 5 Feb. 2020

Word History

Etymology

International Scientific Vocabulary inosinic acid (the acid C10H13N4O8P; inosinic, from Greek in-, is sinew + International Scientific Vocabulary -ose entry 2 + -in entry 1 + -ic entry 1) + -ine entry 2

First Known Use

1911, in the meaning defined above

Time Traveler
The first known use of inosine was in 1911

Dictionary Entries Near inosine

Cite this Entry

“Inosine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/inosine. Accessed 28 Nov. 2024.

Medical Definition

inosine

noun
ino·​sine ˈin-ə-ˌsēn How to pronounce inosine (audio) ˈī-nə- How to pronounce inosine (audio)
-sən
: a crystalline nucleoside C10H12N4O5 that is composed of hypoxanthine and ribose, that in the form of its monophosphate is a biosynthetic precursor of both AMP and its guanosine analog, and that binds to adenine, cytosine, or uracil especially in some transfer RNAs
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