fenfluramine

noun

fen·​flur·​amine ˌfen-ˈflu̇r-ə-ˌmēn How to pronounce fenfluramine (audio)
: an anorectic amphetamine derivative C12H16F3N with little stimulant effect on the central nervous system formerly used in the form of its hydrochloride to treat obesity but no longer used due to its association with heart valve disease see fen-phen sense 1

Examples of fenfluramine in a Sentence

Recent Examples on the Web
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These cases were reported with fenfluramine or the related dexfenfluramine alone, but never with phentermine alone (phentermine remains on the market). Dr. Keith Roach, oregonlive, 28 Aug. 2023 Subsequent studies estimated that seven out of 10,000 people who took fenfluramine or fen-phen for less than four months developed valve disease, while 35 in 10,000 people who took fenfluramine or fen-phen for more than four months developed valve disease. Dr. Keith Roach, oregonlive, 28 Aug. 2023 So, why not just use fenfluramine in humans? Jennifer Walter, Discover Magazine, 11 Dec. 2019 One of the drugs in the combination known as fen-phen (a combination of fenfluramine and phentermine) was famously withdrawn in 1997 for damaging patients' heart valves. Karen Weintraub, USA TODAY, 20 Feb. 2023 Sure enough, fenfluramine activated the brain's receptors with a flood of serotonin, just like MDMA. Jennifer Walter, Discover Magazine, 11 Dec. 2019 In 1997, weight loss drug fenfluramine/phentermine (fen-phen) was pulled off the market after it was found to cause heart problems. Alexandra Ossola, Quartz, 19 June 2022 Belviq is chemically similar to fenfluramine, which was removed from the market after the fen-phen heart valve problems. John Fauber, Milwaukee Journal Sentinel, 22 Aug. 2021 Lingering safety doubts persist after several high-profile withdrawals, including the combination drug fenfluramine/phentermine in 1997, Meridia (sibutramine) in 2010, and Belviq (lorcaserin) in early 2020. Joshua Cohen, Forbes, 5 June 2021

Word History

Etymology

fen- (alteration of phen-) + -flur- (alteration of fluor-) + amine

First Known Use

1964, in the meaning defined above

Time Traveler
The first known use of fenfluramine was in 1964

Dictionary Entries Near fenfluramine

Cite this Entry

“Fenfluramine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/fenfluramine. Accessed 29 Nov. 2024.

Medical Definition

fenfluramine

noun
fen·​flur·​amine ˌfen-ˈflu̇r-ə-ˌmēn How to pronounce fenfluramine (audio)
: an anorectic amphetamine derivative C12H16F3N with little stimulant effect on the central nervous system formerly used in the form of its hydrochloride to treat obesity but no longer used due to its association with heart valve disease see dexfenfluramine, fen-phen sense 1
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