angiotensin

noun

an·​gio·​ten·​sin ˌan-jē-ō-ˈten(t)-sən How to pronounce angiotensin (audio)
: either of two forms of a kinin of which one has marked vasoconstrictive action
also : a synthetic amide derivative of the physiologically active form used to treat some forms of hypotension

Examples of angiotensin in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Avoid medications that increase risk, such as certain angiotensin converting enzyme (ACE) inhibitors, lithium, and Claravis (isotretinoin). —Mark Gurarie, Verywell Health, 18 Sep. 2024 Instead, they are used after ACE inhibitors, angiotensin receptor blockers (ARBs), and calcium channel blockers (CCBs). —Ayesha Gulzar, Verywell Health, 18 July 2024 People who take medications such as diuretics, anticoagulants, ACE inhibitors or ARBs (angiotensin receptor blockers) to manage cardiovascular issues should also be careful, Tsourounis said, because ibuprofen stresses the kidneys and the heart. —Melinda Wenner Moyer, San Diego Union-Tribune, 9 Apr. 2024 The company’s intravenous drug, TXA127, is a pharmaceutical version of the naturally occurring peptide angiotensin-(1-7), and the company had spent years developing it as a treatment for diseases in which the renin-angiotensin system was out of kilter. —Damian Garde, STAT, 10 June 2020 See all Example Sentences for angiotensin 

Word History

Etymology

angiotonin, an earlier name for the substance (from angio- + Greek tónos "stretching, strain, tension," alluding to its pressor effect + -in entry 1) + hypertensin, a synonymous name, from hypertens(ion) + -in entry 1, after Spanish hipertensina — more at tone entry 1

Note: The term angiotonin was introduced by the American physiologist Irvine H. Page (1901-91) and biochemist Oscar M. Helmer in "A crystalline pressor substance (angiotonin) resulting from the reaction between renin and renin activator," Journal of Experimental Medicine, vol. 71, No. 1 (January 1, 1940), pp. 29-42. The etymology is stated explicitly: "For this substance we suggest the name 'angiotonin' [Greek ἀγγεῖον, blood vessel, + τόνος (τείνω), strain]" (p. 29). Spanish hipertensina was introduced by the Argentine physiologist Eduardo Braun-Menéndez (1903-59) and coworkers in "La sustancia hipertensora de la sangre del riñón isquemiado," Revista de la Sociedad Argentina de Biología, vol. 15 (1939), pp. 420-25. Page and Braun-Menéndez later agreed to merge the two synonymous names into angiotensin; see "Suggested Revision of Nomenclature—Angiotensin," Science, vol. 127, Issue 3292 (January 31, 1958), p. 242.

First Known Use

1958, in the meaning defined above

Time Traveler
The first known use of angiotensin was in 1958

Phrases Containing angiotensin

Dictionary Entries Near angiotensin

Angiospermae

angiotensin

angiotensin converting enzyme

See More Nearby Entries 

Cite this Entry

“Angiotensin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/angiotensin. Accessed 29 Nov. 2024.

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Medical Definition

angiotensin

noun
an·​gio·​ten·​sin ˌan-jē-ō-ˈten(t)-sən How to pronounce angiotensin (audio)
1
: either of two forms of a kinin of which one has marked physiological activity and the other is its physiologically inactive precursor
especially : angiotensin ii
2
: a synthetic amide derivative of angiotensin II used to treat some forms of hypotension

More from Merriam-Webster on angiotensin

Britannica.com: Encyclopedia article about angiotensin

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