amantadine
noun
aman·ta·dine
ə-ˈman-tə-ˌdēn 
: a drug used especially as the hydrochloride C10H17N·HCl to prevent infection (as by an influenza virus) by interfering with virus penetration into host cells
Examples of amantadine in a Sentence
Recent Examples on the Web
Because of his extensive contacts after a lifetime of advocacy, Waldrep recommended a drug called amantadine, which previously had been used for the flu and had been granted orphan drug status by the FDA to treat Parkinson’s patients only a few months earlier.
—
Dallas News, 29 Sep. 2022
The antiviral drug amantadine, for instance, was originally developed for influenza, but was repurposed as a Parkinson's therapy.
—Annette Bakker, Fortune, 5 July 2021
His main approach has been to target the mutation in the M2 channel that created resistance to amantadine and rimantadine.
—Neil Savage, Scientific American, 18 Sep. 2019
What’s more, the flu virus has developed resistance to oseltamivir and to an older drug, amantadine.
—Kai Kupferschmidt, Science | AAAS, 23 Oct. 2019
Nearly all the viruses in circulation around the globe had a mutation that rendered amantadine and rimantadine—the two adamantanes used to treat flu, which work by blocking a particular step in viral replication—completely useless.
—Neil Savage, Scientific American, 18 Sep. 2019
There are only two other classes of flu drugs, neuraminidase inhibitors (drugs like Tamiflu, Relenza, Rapivab) and the adamantane drugs (amantadine and rimantadine).
—Helen Branswell, STAT, 27 June 2018
Influenza viruses developed resistance long ago to the first two antiviral flu drugs, amantadine and rimantadine.
—NBC News, 26 June 2018
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Dallas News, 29 Sep. 2022
The antiviral drug amantadine, for instance, was originally developed for influenza, but was repurposed as a Parkinson's therapy.
—Annette Bakker, Fortune, 5 July 2021
His main approach has been to target the mutation in the M2 channel that created resistance to amantadine and rimantadine.
—Neil Savage, Scientific American, 18 Sep. 2019
What’s more, the flu virus has developed resistance to oseltamivir and to an older drug, amantadine.
—Kai Kupferschmidt, Science | AAAS, 23 Oct. 2019
Nearly all the viruses in circulation around the globe had a mutation that rendered amantadine and rimantadine—the two adamantanes used to treat flu, which work by blocking a particular step in viral replication—completely useless.
—Neil Savage, Scientific American, 18 Sep. 2019
There are only two other classes of flu drugs, neuraminidase inhibitors (drugs like Tamiflu, Relenza, Rapivab) and the adamantane drugs (amantadine and rimantadine).
—Helen Branswell, STAT, 27 June 2018
Influenza viruses developed resistance long ago to the first two antiviral flu drugs, amantadine and rimantadine.
—NBC News, 26 June 2018
Dictionary Entries Near amantadine
Cite this Entry
“Amantadine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/amantadine. Accessed 1 Dec. 2024.
Copy CitationMedical Definition
amantadine
noun
aman·ta·dine
ə-ˈmant-ə-ˌdēn
: a drug administered orally especially in the form of its hydrochloride C10H17N·HCl to prevent infection (as by the virus causing influenza A) by interfering with virus penetration into host cells and in the treatment of Parkinson's disease see symmetrel
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