actin

1 of 2

noun

ac·​tin ˈak-tən How to pronounce actin (audio)
: a cellular protein found especially in microfilaments (such as those comprising myofibrils) and active in muscular contraction, cellular movement, and maintenance of cell shape

actin-

2 of 2

combining form

variants or actini- or actino-
1
: having a radiate form
actinolite
2
: actinic radiation (such as X-rays)
actinometer

Examples of actin in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Noun
In turn, the cytoskeleton relies on a type of actin protein, called filamentous or F-actin. New Atlas, 2 Nov. 2024 In healthy muscle, small threadlike components called actin and myosin neatly line up next to each other. Cindy Kuzma, SELF, 29 Oct. 2024 Those cells reveal some eukaryote-like features (opens a new tab), such as a cytoskeleton built with the protein actin. Quanta Magazine, 28 Oct. 2024 One color shows the cell nucleus (to mark where each cell is) and others show the structural component actin (which determines the shape of the cell) and the microtubules that are part of the communication and transport network within a cell. Eva Amsen, Forbes, 17 Oct. 2024 Dormant NSCs in Drosophila have a protrusion that extends from the cell body; the researchers had recently demonstrated that the protrusion is enriched with actin microfilaments. New Atlas, 15 Aug. 2024 The arrangement of actin within cells is regulated by another type of protein called formin, which accelerates the assembly of a particular actin, filamentous actin (f-actin). New Atlas, 15 Aug. 2024 Rome proposes that vaults might be ferrying the blueprint for actin to the construction sites. Betsy Hanson, Discover Magazine, 11 Nov. 2019 One place where vaults seem to clump together is where the cell is building long fibers of the protein actin that make up part of the cell’s internal skeleton. Betsy Hanson, Discover Magazine, 11 Nov. 2019

Word History

Etymology

Noun

probably from act entry 2 or act(ivate) + -in entry 1

Combining form

borrowed from Greek aktino-, from aktīn-, aktís "ray, beam, spoke of a wheel"

Note: The Greek word has traditionally been linked with Sanskrit aktú-, conjectured to mean "twilight," and with Germanic *uŋhtwōn- "last part of the night, dawn," whence Old English ūhte "twilight, daybreak," Old High German uohta "dawn," Old Norse ōtta "last part of the night," Gothic uhtwo "dawn," from Indo-European *n̥kwt-u-n-, a zero-grade derivative of *nokwt-/*nekwt- "night" (see night entry 1). Robert Beekes (Etymological Dictionary of Greek, Leiden, 2009) rejects this connection on the grounds that aktís "shows no trace of a labiovelar." In reference to actinic radiation, the formative actino- was probably first used by John herschel in actinometer (1833).

First Known Use

Noun

1942, in the meaning defined above

Time Traveler
The first known use of actin was in 1942

Dictionary Entries Near actin

Cite this Entry

“Actin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/actin. Accessed 28 Nov. 2024.

Kids Definition

actin

noun
ac·​tin ˈak-tən How to pronounce actin (audio)
: a protein of muscle that with myosin is active in muscular contraction

Medical Definition

actin

noun
ac·​tin ˈak-tən How to pronounce actin (audio)
: a protein found especially in microfilaments (as those comprising myofibrils) and active in muscular contraction, cellular movement, and maintenance of cell shape see f-actin, g-actin

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